Objective: This study assessed blood C-reactive protein (CRP), fibrinogen,\nprocalcitonin, and CA125 levels and determined whether they have an effect\non pregnancy. Material & Methods: Between Feb. and Sep. 2018, 50 consecutive\nwomen who had their first frozen embryo transfer at a tertiary referral\nIVF center in Turkey were included in the study. Serum samples were collected\non the second day of the cycle and on the transfer day. The women\nwere divided into two groups based on the results of pregnancy outcome:\npregnant (group 1) and non-pregnant (group 2). Blood CRP, fibrinogen,\nprocalcitonin, and CA125 levels were compared between the groups. Results:\nThere were no statistically significant differences between the groups according\nto CA125, CRP, fibrinogen, and procalcitonin levels at the beginning of\nthe cycle and on the transfer day. In comparison with levels at the beginning\nof the cycle and on the transfer day, fibrinogen and CRP were significantly\nhigher on the transfer day than at the beginning of the cycle. Procalcitonin\nwas significantly higher on the transfer day than at the beginning of the cycle\nin group 1. However, there was no statistically significant difference between\nthe transfer day and the beginning of the cycle in group 2. Conclusions:\nHowever, the fibrinogen, CRP and procalcitonin levels were significantly\nhigher on the transfer day than at the beginning of the cycle. The results indicated\nthat acute phase reactants or CA125 should not be used to determine\nthe time of embryo transfer or predict pregnancy.
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